Macrovascular complications of diabetes are those that affect the
large blood vessels. Diabetes damages the lining of blood vessels, causing them
to narrow, which decreases the blood supply and eventually causes injury to the
affected area.
- When blood vessels that supply the brain and
heart are affected, a heart attack or stroke may occur.
- When the
large blood vessels in the legs are affected, problems with blood circulation
to the legs and feet may develop, causing changes in skin color, decreased
sensation, and leg cramps (peripheral arterial disease).
Keeping blood sugar levels tightly within a safe range helps
prevent macrovascular disease.
